SCHEMBL29975243

SCHEMBL29975243

O=[N+]([O-])c1cccc(Cl)c1CCl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TSHR P16473 2/20 0.53
KDM4E B2RXH2 2/20 0.52
LMNA P02545 2/20 0.49
HPGD P15428 2/20 0.47
TDP1 Q9NUW8 4/20 0.47
MAPT P10636 3/20 0.46
MAPK1 P28482 2/20 0.46
POLB P06746 1/20 0.46
GPR35 Q9HC97 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C19 P33261 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10756135 1.00 ALDH1A1 (0.53) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL11318163 0.88 ALDH1A1 (0.61) ALDH1A1TSHRKDM4EHPGDTDP1
SCHEMBL7784647 0.85 ALDH1A1 (0.54) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL4146683 0.83 ALDH1A1 (0.51) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL31148323 0.83 ALDH1A1 (0.51) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL5681342 0.83 ALDH1A1 (0.51) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL6889978 0.83 ALDH1A1 (0.51) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL4715285 0.83 ALDH1A1 (0.55) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL844236 0.83 ALDH1A1 (0.51) ALDH1A1TSHRKDM4ELMNAHPGD
SCHEMBL6557896 0.81 ALDH1A1 (0.61) ALDH1A1TSHRKDM4ELMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754543-B Method for separating high-boiling-point isomer by utilizing gas phase adsorption of hierarchical pore silicon molecular sieve 南京工业大学 2022-09-20 CN disclosed