Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31148323 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL3420889 | 0.86 | TDP1 (0.54) | ALDH1A1KDM4EHPGDTDP1MAPT | |
| SCHEMBL5739265 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL10756135 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL29975243 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL9128320 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL6889978 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL4715285 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL4146683 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHPGDTDP1 | |
| SCHEMBL5681342 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179043-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-06-05 | — | — | US | disclosed |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250154124-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-15 | — | — | US | disclosed |
| WO-2023158769-A1 | PROCESSES FOR THE PREPARATION OF N-(1- METHYLCYCLOPROPYL)-2-(3 -PYRIDINYL)-2H- INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORPORATION (US) | 2023-08-24 | — | — | WO | disclosed |
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| WO-2018138692-A1 | NOVEL FUNGICIDAL CARBAMATE COMPOUNDS | INSECTICIDES (INDIA) LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |
| US-9796726-B2 | Dihydroquinoline pyrazolyl compounds | HOFFMANN-LA ROCHE INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-9796702-B2 | Dihydroquinoline pyrazolyl compounds | HOFFMANN-LA ROCHE INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-9790200-B2 | Dihydroquinoline pyrazolyl compounds | HOFFMANN-LA ROCHE INC. (US) | 2017-10-17 | — | — | US | disclosed |
| EP-3212630-A1 | NEW DIHYDROQUINOLINE PYRAZOLYL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2017-09-06 | — | — | EP | disclosed |
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| EP-1192121-A1 | METHOD FOR PRODUCING 2-HALO-6-NITROBENZOIC ACIDS | Bayer Aktiengesellschaft (DE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076951-A1 | METHOD FOR PRODUCING 2-HALO-6-NITROBENZOIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-21 | — | — | WO | disclosed |
| CN-1094044-A | Imidazopyridine | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | CN | disclosed |
| US-4692182-A | Herbicidal isoxazolidinone derivatives | FMC CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| US-4390540-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1983-06-28 | — | — | US | disclosed |
| EP-0000718-B1 | QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS AND THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-03-24 | — | — | EP | disclosed |
| EP-0046267-A1 | Imidazoquinazoline derivatives, their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-02-24 | — | — | EP | disclosed |
| US-4256748-A | INOTROPIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1981-03-17 | — | — | US | disclosed |
| EP-0000718-A2 | Quinazoline derivatives, process for their preparation, pharmaceutical preparations and their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179043-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | ACHE, CYP4B1, CYP3A4 | ALDH1A1 1130/4885KDM4E 1170/4885LMNA 402/4885 |
| US-20250154124-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | ACHE, CYP4B1, CYP3A4 | ALDH1A1 1130/4885KDM4E 1170/4885LMNA 402/4885 |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | ACHE, CYP4B1, CYP3A4 | ALDH1A1 1130/4885KDM4E 1170/4885LMNA 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.