Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16153704 | 0.85 | SLC1A2 (0.58) | ADRA2AADRA2BADRA2CGABRA5SLC1A2 | |
| SCHEMBL16058521 | 0.78 | GRIN2B (0.44) | ADRA2AADRA2BADRA2CNPC1ALDH1A1 | |
| SCHEMBL27531380 | 0.78 | IDO1 (0.50) | GABRA5NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28795511 | 0.78 | IDO1 (0.50) | GABRA5NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL13359015 | 0.77 | HPGD (0.44) | GABRA5NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL14685085 | 0.76 | NPC1 (0.50) | ADRA2AADRA2BADRA2CSLC1A2NPC1 | |
| SCHEMBL30931673 | 0.76 | LOXL2 (0.55) | ADRA2AADRA2BADRA2CMAOBMPO | |
| SCHEMBL28799362 | 0.74 | NPC1 (0.53) | GABRA5NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10055039 | 0.74 | NPC1 (0.68) | GABRA5NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28491484 | 0.74 | ALDH1A1 (0.43) | GABRA5NPC1ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257052-A1 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF | PFIZER INC. (US) | 2025-08-14 | — | — | US | disclosed |
| US-12319669-B2 | GLP-1 receptor agonists and uses thereof | PFIZER INC. (US) | 2025-06-03 | — | — | US | disclosed |
| US-20240034725-A1 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF | PFIZER INC. (US) | 2024-02-01 | — | — | US | disclosed |
| US-11802121-B2 | GLP-1 receptor agonists and uses thereof | PFIZER INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230124938-A1 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF | PFIZER INC. (US) | 2023-04-20 | — | — | US | disclosed |
| US-11512070-B2 | GLP-1 receptor agonists and uses thereof | PFIZER INC. (US) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512070-B2 | GLP-1 receptor agonists and uses thereof | GLP1R, GIPR, GPR119 | ADRA2A 290/4885ADRA2B 383/4885ADRA2C 405/4885 |
| US-20250257052-A1 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF | GLP1R, GIPR, GPR119 | ADRA2A 290/4885ADRA2B 383/4885ADRA2C 405/4885 |
| US-12319669-B2 | GLP-1 receptor agonists and uses thereof | GLP1R, GIPR, GPR119 | ADRA2A 290/4885ADRA2B 383/4885ADRA2C 405/4885 |
| US-11802121-B2 | GLP-1 receptor agonists and uses thereof | GLP1R, GIPR, GPR119 | ADRA2A 290/4885ADRA2B 383/4885ADRA2C 405/4885 |
| US-20240034725-A1 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF | GLP1R, GIPR, GPR119 | ADRA2A 290/4885ADRA2B 383/4885ADRA2C 405/4885 |
| US-20230124938-A1 | GLP-1 RECEPTOR AGONISTS AND USES THEREOF | GLP1R, GIPR, GPR119 | ADRA2A 290/4885ADRA2B 383/4885ADRA2C 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.