Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.41 |
| ▸ | IL1B | P01584 | 3/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182190 | 0.97 | CRHR1 (0.44) | CRHR1IL1BEHMT2IDO1TDO2 | |
| SCHEMBL26438937 | 0.85 | IL1B (0.54) | IL1BIDO1TDO2SCN9ANLRP3 | |
| SCHEMBL29326810 | 0.85 | IL1B (0.54) | IL1BIDO1TDO2SCN9ANLRP3 | |
| SCHEMBL27182175 | 0.75 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL29326134 | 0.73 | TRPV1 (0.43) | CRHR1 | |
| SCHEMBL26439193 | 0.72 | NLRP3 (0.56) | CRHR1IL1BSCN9ANLRP3 | |
| SCHEMBL29326825 | 0.72 | BCDIN3D (0.47) | IL1BNLRP3 | |
| SCHEMBL26092539 | 0.70 | IL1B (0.57) | CRHR1IL1BNLRP3 | |
| SCHEMBL26092532 | 0.70 | IL1B (0.57) | CRHR1IL1BNLRP3 | |
| SCHEMBL29326670 | 0.70 | NLRP3 (0.54) | CRHR1IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022230912-A1 | SUBSTITUTED TRIAZINE COMPOUND | アステラス製薬株式会社 | 2022-11-03 | — | — | WO | disclosed |