Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 1.00 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.75 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71905 | 1.00 | NNMT (1.00) | NNMTMKNK1MKNK2SMN1; SMN2SIRT6 | |
| Hydrochloric Acid SCHEMBL5013391 | 0.98 | NNMT (0.96) | NNMTMKNK1MKNK2SMN1; SMN2SIRT6 | |
| Hydrochloric Acid SCHEMBL6234386 | 0.98 | NNMT (0.96) | NNMTMKNK1MKNK2SMN1; SMN2SIRT6 | |
| SCHEMBL5013528 | 0.92 | NNMT (0.84) | NNMTMKNK1MKNK2SMN1; SMN2SIRT6 | |
| SCHEMBL18228074 | 0.84 | NNMT (0.72) | NNMTMKNK1MKNK2SMN1; SMN2SIRT6 | |
| SCHEMBL1515510 | 0.84 | NNMT (0.72) | NNMTMKNK1MKNK2SMN1; SMN2SIRT6 | |
| SCHEMBL26034355 | 0.83 | NNMT (0.68) | NNMTMKNK1MKNK2SMN1; SMN2MAPT | |
| SCHEMBL29757598 | 0.82 | NNMT (0.70) | NNMTMKNK1MKNK2SIRT6CA1 | |
| SCHEMBL29514668 | 0.82 | NNMT (0.70) | NNMTMKNK1MKNK2SMN1; SMN2SIRT6 | |
| SCHEMBL185291 | 0.82 | NNMT (0.70) | NNMTMKNK1MKNK2SIRT6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151256-A | Novel compounds for the treatment of diseases associated with DUX expression | FACIO知识产权有限公司 | 2022-10-04 | — | — | CN | disclosed |