SCHEMBL29975605

SCHEMBL29975605

C=Cc1cccc(C)c1-c1ccccc1C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MYC P01106 1/20 0.39
TRIM24 O15164 2/20 0.37
TRIM33 Q9UPN9 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
HTR7 P34969 1/20 0.34
NR1H2 P55055 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19609001 0.87 ALDH1A1 (0.61) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL23700154 0.83 MYC (0.44) ALDH1A1TSHRTDP1MYCKDM4E
SCHEMBL7075278 0.79 ALDH1A1 (0.52) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL1666430 0.78 ALDH1A1 (0.59) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL19655033 0.77 ALDH1A1 (0.42) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL31322055 0.77 LMNA (0.55) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL6520322 0.76 ALDH1A1 (0.52) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL28468926 0.76 ALDH1A1 (0.52) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL28252883 0.76 ALDH1A1 (0.40) ALDH1A1TSHRKMT2ALMNAMYC
SCHEMBL31134251 0.76 ALDH1A1 (0.47) ALDH1A1TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073294-A Method for synthesizing axial chiral aryl conjugated diene through asymmetric alfa-C-H olefination reaction and product thereof 杭州师范大学 2022-09-20 CN disclosed