SCHEMBL23700154

SCHEMBL23700154

C=Cc1ccccc1-c1c(C)cccc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.44
HTR7 P34969 2/20 0.42
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
ACHE P22303 1/20 0.36
PDK2 Q15119 1/20 0.36
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
DRD2 P14416 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 1/20 0.33
TP53 P04637 1/20 0.33
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910570 0.84 PDK2 (0.38) ALDH1A1TSHRKDM4ECYP1A2CYP2C19
SCHEMBL29975605 0.83 ALDH1A1 (0.52) MYCHTR7ALDH1A1TSHRKDM4E
SCHEMBL8613228 0.83 ALDH1A1 (0.43) HTR7ALDH1A1TSHRKDM4ECYP1A2
SCHEMBL16166884 0.82 ALDH1A1 (0.39) MYCALDH1A1TSHRKDM4ECYP1A2
SCHEMBL19609001 0.79 ALDH1A1 (0.61) MYCHTR7ALDH1A1TSHRKDM4E
SCHEMBL31734718 0.79 TDP2 (0.39) ALDH1A1TSHRKDM4ECYP1A2CYP2C19
SCHEMBL21875514 0.79 TDP2 (0.39) ALDH1A1TSHRKDM4ECYP1A2CYP2C19
SCHEMBL7086151 0.79 ALDH1A1 (0.36) ALDH1A1TSHRKDM4ECYP1A2CYP2C19
SCHEMBL21125580 0.78 ALDH1A1 (0.39) ALDH1A1TSHRKDM4ECYP1A2CYP2C19
SCHEMBL19655033 0.77 ALDH1A1 (0.42) MYCALDH1A1TSHRKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240336717-A1 FUNCTIONALIZED POLYMERS HAVING THERMORESPONSIVE BEHAVIOR BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2024-10-10 US disclosed
US-12054573-B2 Functionalized polymers having thermoresponsive behavior BRIDGESTONE CORPORATION (JP) 2024-08-06 US disclosed
US-20210238336-A1 FUNCTIONALIZED POLYMERS HAVING THERMORESPONSIVE BEHAVIOR BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2021-08-05 US disclosed