Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 15/20 | 1.00 |
| ▸ | GSK3B | P49841 | 15/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.74 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.74 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.74 |
| ▸ | CDK2 | P24941 | 2/20 | 0.74 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.73 |
| ▸ | CDK1 | P06493 | 3/20 | 0.73 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.73 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CDK14 | O94921 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | CDK4 | P11802 | 1/20 | 0.73 |
| ▸ | SRC | P12931 | 1/20 | 0.73 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.73 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.73 |
| ▸ | CDK11B | P21127 | 1/20 | 0.73 |
| ▸ | CCND1 | P24385 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319809 | 0.90 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL30319807 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL30273058 | 0.85 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL29421607 | 0.84 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL29364210 | 0.76 | GSK3A (0.71) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL30597679 | 0.73 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL29648491 | 0.73 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL30597674 | 0.73 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL30094663 | 0.73 | GSK3A (1.00) | GSK3AGSK3BCDK5CDK5R1CCNE1 | |
| SCHEMBL30319805 | 0.72 | GSK3A (0.76) | GSK3AGSK3BCDK5CDK5R1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466342-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | Institut Pasteur (FR) | 2024-11-27 | — | — | EP | claimed |
| WO-2023139242-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | INSTITUT PASTEUR (FR) | 2023-07-27 | — | — | WO | claimed |
| EP-4466342-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | Institut Pasteur (FR) | 2024-11-27 | — | — | EP | disclosed |
| CN-114521142-B | Compositions and methods for inhibiting and/or treating neurodegenerative diseases and/or clinical conditions thereof | CK雷容股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| EP-4347674-A1 | THERMOREVERSIBLE POLYMERS AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2024-04-10 | — | — | EP | disclosed |
| EP-4329748-A1 | INDIRUBIN COMPOUNDS AND METHODS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023139242-A1 | METHOD FOR REPROGRAMMING CD8+ T CELLS TO ENHANCE THEIR THERAPEUTIC POTENTIAL AND APPLICATIONS THEREOF | INSTITUT PASTEUR (FR) | 2023-07-27 | — | — | WO | disclosed |
| WO-2022251137-A1 | THERMOREVERSIBLE POLYMERS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-01 | — | — | WO | disclosed |
| WO-2022229986-A1 | INDIRUBIN COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2022-11-03 | — | — | WO | disclosed |