Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985694 | 1.00 | GPBAR1 (0.42) | GPBAR1GAAHPGDKDM4ELMNA | |
| SCHEMBL19805650 | 0.78 | GAA (0.43) | GPBAR1GAAHPGDKDM4ELMNA | |
| SCHEMBL29975711 | 0.78 | GAA (0.43) | GPBAR1GAAHPGDKDM4ELMNA | |
| SCHEMBL19805613 | 0.78 | NPSR1 (0.69) | GPBAR1HPGDKDM4ELMNANPSR1 | |
| SCHEMBL76562 | 0.76 | GAA (0.50) | GAAKDM4ELMNANPSR1ALDH1A1 | |
| SCHEMBL29977085 | 0.76 | MEN1 (0.44) | HPGDKDM4ELMNANPSR1MITF | |
| SCHEMBL19806062 | 0.76 | SDHB (0.59) | GPBAR1HPGDKDM4ELMNANPSR1 | |
| SCHEMBL19805929 | 0.76 | MEN1 (0.44) | HPGDKDM4ELMNANPSR1MITF | |
| SCHEMBL29976648 | 0.75 | LMNA (0.63) | HPGDKDM4ELMNANPSR1MITF | |
| SCHEMBL19805783 | 0.74 | MEN1 (0.42) | HPGDKDM4ELMNANPSR1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |