SCHEMBL29975950

SCHEMBL29975950

CC(C)(C)OC(=O)N[C@H](CCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 6/20 0.57
KMT2A Q03164 1/20 0.56
TLR2 O60603 3/20 0.54
TLR1 Q15399 1/20 0.54
MDM4 O15151 2/20 0.49
TP53 P04637 2/20 0.49
IDO1 P14902 1/20 0.48
KLK7 P49862 1/20 0.46
KLK5 Q9Y337 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7392221 1.00 MDM2 (0.57) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL7815145 1.00 MDM2 (0.57) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL30441695 1.00 MDM2 (0.57) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL17669898 1.00 MDM2 (0.57) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL29400691 1.00 MDM2 (0.57) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL2267346 0.97 KMT2A (0.58) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL29401707 0.97 KMT2A (0.58) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL12040103 0.97 KMT2A (0.58) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL999302 0.97 KMT2A (0.58) MDM2KMT2ATLR2TLR1MDM4
SCHEMBL29362262 0.97 KMT2A (0.58) MDM2KMT2ATLR2TLR1MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634174-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-10-22 EP disclosed
EP-4622966-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-10-01 EP disclosed
WO-2024129600-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-06-20 WO disclosed
WO-2024112612-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-05-30 WO disclosed
EP-4069270-A1 MODULATORS OF PROGRAMMED DEATH-LIGAND-1 AND/OR PROGRAMMED DEATH-LIGAND-2 Southern Research Institute (US) 2022-10-12 EP disclosed