Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910485 | 1.00 | GNRHR (0.34) | GNRHRTP53PDE2AMAP3K5 | |
| SCHEMBL30526072 | 0.89 | GNRHR (0.33) | GNRHRTP53PDE2A | |
| SCHEMBL29976245 | 0.89 | GNRHR (0.37) | GNRHRTP53 | |
| SCHEMBL28910497 | 0.89 | GNRHR (0.37) | GNRHRTP53 | |
| SCHEMBL29976060 | 0.80 | SDHB (0.33) | GNRHR | |
| SCHEMBL28910490 | 0.80 | SDHB (0.33) | GNRHR | |
| SCHEMBL23897425 | 0.80 | ALDH1A1 (0.34) | GNRHRTP53 | |
| SCHEMBL29975854 | 0.79 | TGFBR1 (0.33) | — | |
| SCHEMBL28910503 | 0.79 | TGFBR1 (0.33) | — | |
| SCHEMBL28910492 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |