Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985675 | 1.00 | SDHB (0.43) | SDHBPOLBGAAMAPTPDE4A | |
| SCHEMBL20985637 | 0.88 | KMT2A (0.35) | POLBMAPT | |
| SCHEMBL19805945 | 0.87 | POLB (0.34) | SDHBPOLBGAAMAPTPDE4A | |
| SCHEMBL19805943 | 0.85 | SDHB (0.39) | SDHB | |
| SCHEMBL30526095 | 0.85 | SDHB (0.39) | SDHB | |
| SCHEMBL23503516 | 0.82 | S1PR4 (0.33) | — | |
| SCHEMBL29976277 | 0.82 | SDHB (0.58) | SDHBPDE4APDE4B | |
| SCHEMBL19805741 | 0.82 | SDHB (0.58) | SDHBPDE4APDE4B | |
| SCHEMBL30526091 | 0.81 | SDHB (0.33) | SDHB | |
| SCHEMBL19806105 | 0.81 | SDHB (0.33) | SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |