Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SDHB | P21912 | 2/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912281 | 0.88 | EGFR (0.36) | POLBVCPGAAMAPTALDH1A1 | |
| SCHEMBL29976254 | 0.87 | SDHB (0.43) | POLBSDHBGAAMAPTPDE4A | |
| SCHEMBL20985675 | 0.87 | SDHB (0.43) | POLBSDHBGAAMAPTPDE4A | |
| SCHEMBL19806106 | 0.81 | VCP (0.32) | VCP | |
| SCHEMBL19805944 | 0.80 | VCP (0.35) | POLBVCPGAAMAPTALDH1A1 | |
| SCHEMBL21019518 | 0.79 | MGAM (0.35) | VCPGAAMAPTALDH1A1 | |
| SCHEMBL22912304 | 0.79 | HSD17B10 (0.35) | VCPALDH1A1MAPK1 | |
| SCHEMBL22912303 | 0.79 | VCP (0.33) | VCP | |
| SCHEMBL21019945 | 0.78 | BRD4 (0.32) | VCP | |
| SCHEMBL22912269 | 0.78 | PFKFB3 (0.32) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |