Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29976723 | 0.88 | BRPF1 (0.41) | ARBRPF1GAAMEN1KMT2A | |
| SCHEMBL29976315 | 0.81 | KIF11 (0.36) | ARHPGDATMKIF11MAPT | |
| SCHEMBL29976910 | 0.81 | TTR (0.39) | ARKDM4EALDH1A1HPGDSRC | |
| SCHEMBL29976327 | 0.81 | EGLN1 (0.39) | ARMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29976914 | 0.80 | SMN1; SMN2 (0.50) | ARBRPF1GAAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL29977243 | 0.80 | LOXL2 (0.35) | GAAKDM4EALDH1A1HPGDATM | |
| SCHEMBL29976613 | 0.79 | EPHX2 (0.49) | GAAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10519092 | 0.79 | HPGD (0.54) | GAAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29976410 | 0.79 | HPGD (0.54) | GAAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29977058 | 0.78 | KDM4E (0.42) | GAAKDM4EALDH1A1HPGDTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403558-A | Aromatic heterocyclic compound with antitumor activity and preparation method and application thereof | 河南真实生物科技有限公司 | 2022-11-29 | — | — | CN | disclosed |