Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803936 | 0.87 | DBH (0.55) | LMNAHTTKMT2AMAPTKDM4E | |
| SCHEMBL31167041 | 0.85 | KLKB1 (0.43) | LMNACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL31166746 | 0.85 | ALDH1A1 (0.45) | LMNAMAPTALDH1A1GAA | |
| SCHEMBL31167031 | 0.83 | KLKB1 (0.47) | MAPTMAPK10 | |
| SCHEMBL15906155 | 0.80 | MAPT (0.46) | LMNAKMT2AMAPTKDM4EMEN1 | |
| SCHEMBL19471891 | 0.79 | TLR7 (0.45) | LMNAKDM4EALDH1A1GAA | |
| SCHEMBL28817529 | 0.79 | MAPT (0.63) | LMNAKMT2AMAPTKDM4EMEN1 | |
| SCHEMBL4326721 | 0.79 | PDE4B (0.61) | MAPTALDH1A1 | |
| SCHEMBL9752787 | 0.78 | POLB (0.63) | MAPTKDM4EALDH1A1THRB | |
| SCHEMBL28159383 | 0.77 | CA2 (0.57) | LMNATSHRHTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |