Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21219198 | 0.77 | ALDH1A1 (0.41) | S1PR4ALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL4420431 | 0.77 | L3MBTL1 (0.42) | S1PR4NPC1ALDH1A1MAPTHTT | |
| SCHEMBL27173079 | 0.77 | CA12 (0.46) | S1PR4ALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL28541140 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL21815478 | 0.75 | MEN1 (0.47) | NPC1ALDH1A1MAPTHTTPOLB | |
| SCHEMBL28455212 | 0.75 | MAPT (0.38) | S1PR4NPC1ALDH1A1MAPTPOLB | |
| SCHEMBL27853767 | 0.75 | EGFR (0.44) | ALDH1A1MAPTLMNA | |
| SCHEMBL28380826 | 0.75 | TSHR (0.39) | S1PR4ALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL28354485 | 0.75 | TSHR (0.39) | ALDH1A1MAPTPOLBRAB9ALMNA | |
| SCHEMBL27208962 | 0.75 | MAPT (0.40) | S1PR4ALDH1A1MAPTPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113476619-B | A kind of 18 F-labeled nano antibody probe and preparation method and application thereof | 上海交通大学医学院附属仁济医院 | 2022-11-29 | — | — | CN | claimed |
| CN-113476619-B | A kind of 18 F-labeled nano antibody probe and preparation method and application thereof | 上海交通大学医学院附属仁济医院 | 2022-11-29 | — | — | CN | disclosed |