Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542067 | 1.00 | MAPT (0.38) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL29746291 | 0.84 | MAPT (0.38) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL26613504 | 0.84 | MAPT (0.38) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL29975888 | 0.83 | MAOA (0.41) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL28555386 | 0.83 | MAOA (0.41) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL28537641 | 0.80 | MAPT (0.35) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL29976034 | 0.80 | MAPT (0.35) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL26613492 | 0.78 | ALDH1A1 (0.47) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL26802173 | 0.78 | MEN1 (0.41) | MAPTKMT2AMEN1CYP1A2TDP1 | |
| SCHEMBL1069807 | 0.77 | TACR1 (0.49) | KMT2AMEN1CYP1A2TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409253-B | Method for synthesizing chiral alpha-tertiary amine by catalytic kinetic resolution | 上海科技大学 | 2022-11-29 | — | — | CN | disclosed |