Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473882 | 1.00 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2HTR1AAPLNR | |
| SCHEMBL474102 | 0.84 | HTR2A (0.46) | SLC6A4HTR2AKCNH2HTR1AMEN1 | |
| SCHEMBL11530709 | 0.82 | RELA (0.48) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11530716 | 0.82 | RELA (0.48) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4519124 | 0.82 | KDM4E (0.37) | SLC6A4HTR2AKCNH2HTR1AMEN1 | |
| SCHEMBL4510419 | 0.82 | ALDH1A1 (0.53) | SLC6A4HTR2AKCNH2HTR1AAPLNR | |
| SCHEMBL8340513 | 0.82 | SLC6A4 (0.47) | SLC6A4HTR2AKCNH2HTR1AAPLNR | |
| SCHEMBL2060421 | 0.81 | HTR2A (0.47) | HTR2AAPLNRCA12CA1CA2 | |
| SCHEMBL1391304 | 0.81 | NQO1 (0.46) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3719649 | 0.81 | EPHX2 (0.42) | SLC6A4HTR2AHTR1AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4469444-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023138684-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |