Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977942 | 0.90 | TLR7 (0.48) | MAOBPOLBBCL2L1 | |
| SCHEMBL24733009 | 0.88 | MAOB (0.48) | MAOBHTR6SMN1; SMN2SIGMAR1ACP1 | |
| SCHEMBL29808930 | 0.88 | MAOB (0.48) | MAOBHTR6SMN1; SMN2SIGMAR1ACP1 | |
| SCHEMBL9601993 | 0.80 | CYP11B1 (0.50) | POLBSMN1; SMN2HTT | |
| SCHEMBL29977556 | 0.79 | LMNA (0.38) | MAOBNPC1POLBSMN1; SMN2HTT | |
| SCHEMBL29977341 | 0.79 | MC4R (0.47) | MAOBNPC1HTR6POLBSIGMAR1 | |
| SCHEMBL29809478 | 0.78 | TLR7 (0.57) | POLB | |
| SCHEMBL29977597 | 0.78 | TLR7 (0.57) | POLB | |
| SCHEMBL24732765 | 0.78 | TLR7 (0.57) | POLB | |
| SCHEMBL24732850 | 0.77 | HRH3 (0.50) | MAOBNPC1POLBSMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |