Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | ACP1 | P24666 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808930 | 1.00 | MAOB (0.48) | MAOBHTR6ACP1HTR1AHTR7 | |
| SCHEMBL29977341 | 0.91 | MC4R (0.47) | MAOBHTR6ACP1HTR1AHTR7 | |
| SCHEMBL29977138 | 0.88 | MAOB (0.41) | MAOBHTR6ACP1HTR1ASIGMAR1 | |
| SCHEMBL29977696 | 0.88 | CACNB4 (0.46) | PRMT6KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29808887 | 0.87 | TLR7 (0.54) | MAOBHTR6PRMT6LMNA | |
| SCHEMBL24732579 | 0.87 | TLR7 (0.54) | MAOBHTR6PRMT6LMNA | |
| SCHEMBL9601993 | 0.86 | CYP11B1 (0.50) | LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL29977856 | 0.85 | METAP2 (0.40) | HTR6PRMT6KDM4EALDH1A1LMNA | |
| SCHEMBL24732850 | 0.84 | HRH3 (0.50) | MAOBHTR1ALMNAMAPTHPGD | |
| SCHEMBL29809072 | 0.84 | L3MBTL1 (0.46) | MAOBHTR6MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |