Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808930 | 0.91 | MAOB (0.48) | HTR1AHTR7NCF1MAOBHTR6 | |
| SCHEMBL24733009 | 0.91 | MAOB (0.48) | HTR1AHTR7NCF1MAOBHTR6 | |
| SCHEMBL29976933 | 0.88 | TLR7 (0.54) | MC4RHRH4HTR1AHTR7NCF1 | |
| SCHEMBL9601993 | 0.83 | CYP11B1 (0.50) | LMNAPOLB | |
| SCHEMBL29977696 | 0.81 | CACNB4 (0.46) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29809072 | 0.79 | L3MBTL1 (0.46) | MAOBHTR6 | |
| SCHEMBL29977138 | 0.79 | MAOB (0.41) | HTR1AMAOBHTR6ACP1HTR1D | |
| SCHEMBL29977334 | 0.78 | HTT (0.42) | MAOBHTR6MAPTLMNAPOLB | |
| SCHEMBL24732579 | 0.78 | TLR7 (0.54) | MAOBHTR6LMNAPOLB | |
| SCHEMBL29808887 | 0.78 | TLR7 (0.54) | MAOBHTR6LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |