Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NQO2 | P16083 | 9/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671109 | 1.00 | POLB (0.48) | POLBNQO2TLR8KDM4EALDH1A1 | |
| SCHEMBL27972111 | 0.88 | POLB (0.44) | POLBNQO2TLR8KDM4EALDH1A1 | |
| SCHEMBL28572078 | 0.85 | POLB (0.44) | POLBNQO2TLR8KDM4EALDH1A1 | |
| SCHEMBL28900290 | 0.78 | POLB (0.44) | POLBNQO2TLR8KDM4EALDH1A1 | |
| SCHEMBL27382658 | 0.76 | NQO1 (0.60) | POLBNQO2KDM4EALDH1A1HPGD | |
| SCHEMBL9709536 | 0.76 | ALDH1A1 (0.51) | POLBNQO2KDM4EALDH1A1HPGD | |
| SCHEMBL28215106 | 0.76 | TLR8 (0.56) | POLBNQO2TLR8KDM4EALDH1A1 | |
| SCHEMBL6972381 | 0.75 | NQO2 (0.63) | POLBNQO2TLR8KDM4EALDH1A1 | |
| SCHEMBL16671341 | 0.75 | KDM4E (0.39) | POLBTLR8KDM4EALDH1A1GLA | |
| SCHEMBL26749714 | 0.74 | ALDH1A1 (0.62) | POLBNQO2KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158340-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2024-05-16 | — | — | US | disclosed |
| WO-2022235875-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SαAME | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158340-A1 | PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME | AHR, CBR3, AADAC | POLB 2335/4885NQO2 220/4885TLR8 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.