Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 4/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671341 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL12014805 | 0.77 | NQO2 (0.51) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL29977206 | 0.76 | POLB (0.48) | ALDH1A1KDM4EHPGDKMT2ANQO2 | |
| SCHEMBL16671109 | 0.76 | POLB (0.48) | ALDH1A1KDM4EHPGDKMT2ANQO2 | |
| SCHEMBL8976427 | 0.75 | NQO1 (0.53) | ALDH1A1KDM4EHPGDNQO2NQO1 | |
| SCHEMBL29954752 | 0.71 | HPGDS (0.46) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL30228371 | 0.70 | NQO2 (0.67) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL7781701 | 0.70 | NQO2 (0.53) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL6239156 | 0.70 | NQO2 (0.67) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL29919905 | 0.69 | NQO1 (0.67) | ALDH1A1KDM4EHPGDMCHR1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | claimed |