Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978367 | 0.93 | SMN1; SMN2 (0.43) | MAPTLMNATP53HDAC4SMN1; SMN2 | |
| SCHEMBL29978122 | 0.90 | PRMT5 (0.44) | MAPTLMNATP53HPGDTDP1 | |
| SCHEMBL29977954 | 0.89 | KMT2A (0.47) | MAPTLMNAHDAC4SMN1; SMN2HTT | |
| SCHEMBL29978125 | 0.89 | KMT2A (0.48) | MAPTHDAC4ALDH1A1KDM4EPOLB | |
| SCHEMBL29978433 | 0.89 | HDAC4 (0.41) | MAPTHDAC4ALDH1A1NPSR1MEN1 | |
| SCHEMBL29978399 | 0.88 | HDAC4 (0.45) | MAPTLMNAHDAC4SMN1; SMN2ALDH1A1 | |
| SCHEMBL29978163 | 0.87 | PRMT5 (0.44) | MAPTLMNATP53TDP1HDAC4 | |
| SCHEMBL29978226 | 0.87 | L3MBTL1 (0.52) | MAPTLMNAHPGDHDAC4GAA | |
| SCHEMBL29978285 | 0.86 | HDAC4 (0.40) | MAPTHDAC4ALDH1A1KDM4EPOLB | |
| SCHEMBL29978357 | 0.85 | HDAC4 (0.49) | LMNAHDAC4SMN1; SMN2POLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |