Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977954 | 0.93 | KMT2A (0.47) | SMN1; SMN2MAPTLMNAHDAC4KMT2A | |
| SCHEMBL29978125 | 0.93 | KMT2A (0.48) | MAPTHDAC4KMT2AATMMEN1 | |
| SCHEMBL29978433 | 0.93 | HDAC4 (0.41) | IDO1TDO2MAPTHDAC4KMT2A | |
| SCHEMBL29977951 | 0.93 | MAPT (0.40) | SMN1; SMN2MAPTTP53LMNAHDAC4 | |
| SCHEMBL29978399 | 0.92 | HDAC4 (0.45) | SMN1; SMN2MAPTLMNAHDAC4KMT2A | |
| SCHEMBL29978122 | 0.91 | PRMT5 (0.44) | SMN1; SMN2MAPTTP53LMNAHDAC4 | |
| SCHEMBL29978285 | 0.88 | HDAC4 (0.40) | MAPTHDAC4KMT2AMEN1ALDH1A1 | |
| SCHEMBL29978226 | 0.88 | L3MBTL1 (0.52) | MAPTLMNAHDAC4KMT2AMEN1 | |
| SCHEMBL29978163 | 0.88 | PRMT5 (0.44) | MAPTTP53LMNAHDAC4KMT2A | |
| SCHEMBL29978357 | 0.87 | HDAC4 (0.49) | SMN1; SMN2LMNAHDAC4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |