Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978721 | 0.95 | DGAT1 (0.45) | DGAT1HDAC6HDAC4HDAC8HDAC1 | |
| SCHEMBL29977864 | 0.93 | DGAT1 (0.40) | DGAT1HDAC6HDAC4HDAC8HDAC1 | |
| SCHEMBL29978771 | 0.91 | POLB (0.46) | DGAT1HDAC6HDAC4HDAC8HDAC1 | |
| SCHEMBL29978258 | 0.89 | NPC1 (0.52) | HDAC6HDAC4HDAC8HDAC1NPC1 | |
| SCHEMBL29978321 | 0.88 | MEN1 (0.47) | HDAC6HDAC4HDAC8HDAC2NPC1 | |
| SCHEMBL29977980 | 0.87 | HDAC4 (0.39) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29977881 | 0.87 | MAPT (0.39) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978205 | 0.87 | HDAC4 (0.47) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978361 | 0.86 | TP53 (0.39) | HDAC6HDAC4HDAC8HDAC1HDAC2 | |
| SCHEMBL29978228 | 0.85 | CYP3A4 (0.44) | HDAC6HDAC4HDAC8HDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |