Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.61 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMO | O15229 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057105 | 1.00 | ALDH1A1 (0.66) | ALDH1A1GAAHTTL3MBTL1PKM | |
| SCHEMBL29978266 | 0.87 | MCOLN2 (0.57) | ALDH1A1GAAHTTL3MBTL1PKM | |
| SCHEMBL29978643 | 0.87 | MCOLN2 (0.57) | ALDH1A1GAAHTTL3MBTL1PKM | |
| SCHEMBL23057225 | 0.87 | GAA (0.64) | ALDH1A1GAAHTTL3MBTL1MCOLN2 | |
| SCHEMBL23057220 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GAAHTTL3MBTL1PKM | |
| SCHEMBL29978501 | 0.85 | L3MBTL1 (0.63) | ALDH1A1GAAHTTL3MBTL1MCOLN2 | |
| SCHEMBL23057187 | 0.84 | ALDH1A1 (0.67) | ALDH1A1GAAHTTL3MBTL1MCOLN2 | |
| SCHEMBL29979656 | 0.83 | ALDH1A1 (0.69) | ALDH1A1GAAHTTL3MBTL1MCOLN3 | |
| SCHEMBL29978040 | 0.83 | MCOLN2 (0.53) | ALDH1A1GAAHTTL3MBTL1PKM | |
| SCHEMBL29979693 | 0.83 | GAA (0.65) | ALDH1A1GAAHTTL3MBTL1MCOLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | ALDH1A1 1368/4885GAA 154/4885HTT 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.