Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 13/20 | 0.43 |
| ▸ | HTR2A | P28223 | 12/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977949 | 0.93 | HDAC4 (0.51) | HDAC4HDAC6PDGFRBHTR2CHTR2A | |
| SCHEMBL29978205 | 0.91 | HDAC4 (0.47) | HDAC4HDAC6HDAC1HDAC8MEN1 | |
| SCHEMBL29978258 | 0.87 | NPC1 (0.52) | HDAC4HDAC6HDAC1HDAC8MEN1 | |
| SCHEMBL29978228 | 0.87 | CYP3A4 (0.44) | HDAC4HDAC6TRPV1HDAC1HDAC8 | |
| SCHEMBL29978038 | 0.86 | HPGD (0.49) | HDAC4HDAC6PDGFRBHDAC1HDAC8 | |
| SCHEMBL29978321 | 0.86 | MEN1 (0.47) | HDAC4HDAC6HDAC8MEN1MAPT | |
| SCHEMBL29978389 | 0.86 | NAMPT (0.46) | HDAC4HDAC6TRPV1MAPTNAMPT | |
| SCHEMBL29978083 | 0.86 | NPC1 (0.47) | HDAC4HDAC6HDAC1HDAC8MEN1 | |
| SCHEMBL29978357 | 0.86 | HDAC4 (0.49) | HDAC4HDAC6HTR2CHTR2AHDAC1 | |
| SCHEMBL29978312 | 0.85 | HDAC6 (0.39) | HDAC4HDAC6HDAC1HDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |