Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RHOC | P08134 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978454 | 0.93 | HDAC6 (0.39) | HDAC4HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL29977993 | 0.92 | HDAC4 (0.46) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29979015 | 0.91 | MEN1 (0.47) | HDAC4HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL29978070 | 0.87 | HDAC4 (0.41) | HDAC4HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL29978476 | 0.86 | HDAC4 (0.50) | HDAC4HDAC6HDAC8LMNATSHR | |
| SCHEMBL29977897 | 0.86 | HDAC4 (0.41) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29977966 | 0.84 | NAMPT (0.43) | HDAC4HDAC6NPSR1 | |
| SCHEMBL29978402 | 0.84 | NPC1 (0.47) | HDAC4HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL29978321 | 0.84 | MEN1 (0.47) | HDAC4HDAC6MEN1KMT2AHDAC8 | |
| SCHEMBL29978688 | 0.83 | RAB9A (0.46) | HDAC4HDAC6HDAC8ALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |