Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978402 | 0.93 | NPC1 (0.47) | NAMPTHDAC4HDAC6TRPM8MAPT | |
| SCHEMBL29979015 | 0.93 | MEN1 (0.47) | NAMPTTRPV1HDAC4HDAC6KDM4E | |
| SCHEMBL29978389 | 0.93 | NAMPT (0.46) | NAMPTEPHX2KCNH2CACNA1CTRPV1 | |
| SCHEMBL29978688 | 0.92 | RAB9A (0.46) | NAMPTHDAC4HDAC6MAPT | |
| SCHEMBL29977979 | 0.92 | HDAC4 (0.47) | HDAC4HDAC6 | |
| SCHEMBL29977836 | 0.91 | KMT2A (0.39) | HDAC4HDAC6MAPT | |
| SCHEMBL29978134 | 0.90 | EPHX2 (0.45) | NAMPTEPHX2TRPV1TRPM8KDM4E | |
| SCHEMBL29979201 | 0.89 | GPR142 (0.45) | TRPV1HDAC4HDAC6MAPTNPSR1 | |
| SCHEMBL29977806 | 0.88 | HDAC6 (0.37) | HDAC4HDAC6 | |
| SCHEMBL29978286 | 0.87 | CYP3A4 (0.44) | TRPV1HDAC4HDAC6MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |