Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306812 | 0.95 | CA12 (0.61) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL1365179 | 0.95 | CA12 (0.61) | CA12CA1CA2ESR1CA7 | |
| Ethyl Benzoate SCHEMBL28451031 | 0.91 | KMT2A (0.56) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL5472654 | 0.86 | RAF1 (0.59) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL1965326 | 0.86 | CA1 (0.73) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL16351874 | 0.86 | CA1 (0.73) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL8463066 | 0.85 | PLAU (0.51) | ALDH1A1SMN1; SMN2HPGDNPC1MAPT | |
| SCHEMBL29649031 | 0.84 | SMN1; SMN2 (0.56) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL8636928 | 0.84 | TSHR (0.57) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL2345404 | 0.84 | HRH2 (0.47) | CA12CA1CA2ESR1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273070-B2 | Organozinc complexes and processes for making and using the same | KNOCHEL PAUL (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9273070-B2 | Organozinc complexes and processes for making and using the same | KNOCHEL PAUL (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) | 2014-01-30 | — | — | US | disclosed |
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) | 2014-01-30 | — | — | US | disclosed |
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20080269514-A1 | Iron or Cobalt-Catalyzed Carbon-Carbon Coupling Reaction of Aryls, Alkenes and Alkines With Copper Reagents | SALTIGO GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269514-A1 | Iron or Cobalt-Catalyzed Carbon-Carbon Coupling Reaction of Aryls, Alkenes and Alkines With Copper Reagents | SALTIGO GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
| WO-2007031511-A1 | NICKEL OR IRON CATALYSED CARBON-CARBON COUPLING REACTION OF ARYLENES, ALKENES AND ALKINES | SALTIGO GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| US-5964919-A | STABILIZING THE ACTIVE ZINC BY SUSPENDING IN A CONTAINER WITH AN SOLVENT SELECT FROM ETHER, HYDROCARBON, AROMATIC HYDROCARABON OR APROTIC SOLVENT UNDER INERT GAS, SEALING THE CONTAINER | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1999-10-12 | — | — | US | disclosed |
| US-5756653-A | REACTING A REDUCING AGENT ON A ZINC SALT | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1998-05-26 | — | — | US | disclosed |
| US-5358546-A | Reacting a zinc compound with a reducting agent | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1993015086-A1 | HIGHLY REACTIVE FORMS OF ZINC AND REAGENTS THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031545-A1 | ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME | ODC1, AOC1, ADH1C | CA12 1323/4885CA1 860/4885CA2 1210/4885 |
| US-20080269514-A1 | Iron or Cobalt-Catalyzed Carbon-Carbon Coupling Reaction of Aryls, Alkenes and Alkines With Copper Reagents | SLC39A14, MAL2, AHR | CA12 241/4885CA1 846/4885CA2 297/4885 |
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | MON2, ZRANB2, GRIA2 | CA12 1754/4885CA1 1518/4885CA2 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.