Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.56 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.56 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043661 | 1.00 | TSHR (0.60) | TSHRMCOLN3MCOLN2MCOLN1TDP1 | |
| SCHEMBL29979713 | 0.89 | MCOLN3 (0.63) | TSHRMCOLN3MCOLN2MCOLN1TDP1 | |
| SCHEMBL23043652 | 0.89 | MCOLN3 (0.63) | TSHRMCOLN3MCOLN2MCOLN1TDP1 | |
| SCHEMBL23043627 | 0.88 | TSHR (0.60) | TSHRMCOLN3MCOLN2MCOLN1RAD52 | |
| SCHEMBL29979719 | 0.88 | TSHR (0.60) | TSHRMCOLN3MCOLN2MCOLN1RAD52 | |
| SCHEMBL14355853 | 0.87 | MCOLN3 (0.71) | TSHRMCOLN3MCOLN2MCOLN1TDP1 | |
| SCHEMBL23043731 | 0.85 | MCOLN3 (0.51) | TSHRMCOLN3MCOLN2MCOLN1TDP1 | |
| SCHEMBL29978540 | 0.85 | MCOLN3 (0.51) | TSHRMCOLN3MCOLN2MCOLN1TDP1 | |
| SCHEMBL14355835 | 0.80 | TSHR (0.52) | TSHRMCOLN3MCOLN2MCOLN1ALDH1A1 | |
| SCHEMBL23057205 | 0.78 | TSHR (0.57) | TSHRMCOLN3MCOLN2MCOLN1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | TSHR 2343/4885MCOLN3 3/4885MCOLN2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.