Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.54 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043652 | 1.00 | MCOLN3 (0.63) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043661 | 0.89 | TSHR (0.60) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL29979203 | 0.89 | TSHR (0.60) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL29979148 | 0.88 | MCOLN3 (0.76) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043616 | 0.88 | MCOLN3 (0.76) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043684 | 0.87 | MCOLN3 (0.63) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL29978469 | 0.87 | MCOLN3 (0.63) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043731 | 0.86 | MCOLN3 (0.51) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL29978540 | 0.86 | MCOLN3 (0.51) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043782 | 0.86 | MCOLN3 (0.59) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | MCOLN3 3/4885L3MBTL1 794/4885PKM 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.