Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.51 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.51 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978540 | 1.00 | MCOLN3 (0.51) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL23057170 | 0.87 | ALDH1A1 (0.49) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL29979713 | 0.86 | MCOLN3 (0.63) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL23043652 | 0.86 | MCOLN3 (0.63) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL29979203 | 0.85 | TSHR (0.60) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL23043661 | 0.85 | TSHR (0.60) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL29979108 | 0.80 | L3MBTL1 (0.46) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL23043707 | 0.80 | L3MBTL1 (0.46) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL23043711 | 0.80 | L3MBTL1 (0.54) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 | |
| SCHEMBL29979705 | 0.80 | L3MBTL1 (0.54) | MCOLN3MCOLN2MCOLN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |