Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 7/20 | 0.52 |
| ▸ | GABRD | O14764 | 7/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.52 |
| ▸ | GABRE | P78334 | 7/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429335 | 1.00 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6239571 | 0.83 | MAOB (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28896611 | 0.83 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29979155 | 0.83 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30861756 | 0.80 | MAOB (0.62) | CYP26B1MAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL29214175 | 0.80 | MAOB (0.62) | CYP26B1MAOBCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL28427113 | 0.79 | CYP1A1 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29978804 | 0.79 | CYP1A1 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15156785 | 0.78 | ESR1 (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18003136 | 0.77 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072604-B | Alpha-aminoamide derivatives and use thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |