Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 8/20 | 0.49 |
| ▸ | GABRD | O14764 | 8/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.49 |
| ▸ | GABRE | P78334 | 8/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896611 | 0.89 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29979155 | 0.89 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18002825 | 0.82 | MAOB (0.59) | MAOBMAOAPRKDC | |
| SCHEMBL30861750 | 0.81 | PTGES (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29214171 | 0.81 | PTGES (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18003612 | 0.81 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6239571 | 0.77 | MAOB (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29979211 | 0.77 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28429335 | 0.77 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18003331 | 0.75 | PRKDC (0.42) | MAOBMAOAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | GABRP 1827/4885GABRD 2985/4885GABRA1 1849/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | GABRP 1827/4885GABRD 2985/4885GABRA1 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.