Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601919 | 0.89 | MAOB (0.54) | MAOBFFAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL18838193 | 0.87 | MAOB (0.46) | MAOBFFAR1CYP2A6CHRM2CHRM4 | |
| SCHEMBL11492249 | 0.87 | HDAC6 (0.52) | MAOBFFAR1CYP2A6PTGESRAB9A | |
| SCHEMBL29214171 | 0.84 | PTGES (0.50) | MAOBCYP2A6CHRM2CHRM4CHRM5 | |
| SCHEMBL30861750 | 0.84 | PTGES (0.50) | MAOBCYP2A6CHRM2CHRM4CHRM5 | |
| SCHEMBL5204810 | 0.84 | MAOB (0.56) | MAOBCYP2A6CHRM2CHRM4CHRM5 | |
| SCHEMBL6901624 | 0.83 | MAOB (0.63) | MAOBFFAR1PTGESCYP26B1ABCG2 | |
| SCHEMBL28896611 | 0.83 | GABRP (0.52) | MAOBCYP2A6CHRM2CHRM4CHRM5 | |
| SCHEMBL29979155 | 0.83 | GABRP (0.52) | MAOBCYP2A6CHRM2CHRM4CHRM5 | |
| SCHEMBL28429335 | 0.83 | GABRP (0.52) | MAOBFFAR1CYP2A6CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063445-A | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118063444-A | Azetidinamide derivatives and uses thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3621957-B1 | FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES | AMBIENT PHOTONICS INC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-108699019-B | Benzofuran derivatives useful in the treatment of central nervous system and other diseases | 华纳巴布科克绿色化学学院有限公司 | 2022-05-10 | — | — | CN | disclosed |
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |