Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 12/20 | 0.44 |
| ▸ | NQO1 | P15559 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22786001 | 0.90 | IDO1 (0.56) | IDO1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL20811248 | 0.80 | IDO1 (0.59) | IDO1NQO1MEN1ALDH1A1MAPT | |
| SCHEMBL103949 | 0.69 | IDO1 (0.53) | IDO1NQO1MEN1ALDH1A1MAPT | |
| SCHEMBL18791100 | 0.68 | IDO1 (0.55) | IDO1NQO1MEN1ALDH1A1MAPT | |
| SCHEMBL18791133 | 0.66 | IDO1 (0.63) | IDO1NQO1MEN1ALDH1A1MAPT | |
| SCHEMBL20811039 | 0.63 | NQO1 (0.76) | IDO1NQO1MEN1ALDH1A1MAPT | |
| Anthraquinone SCHEMBL11698233 | 0.62 | MEN1 (0.71) | IDO1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3618661 | 0.62 | IDO1 (1.00) | IDO1NQO1MEN1ALDH1A1MAPT | |
| SCHEMBL14439353 | 0.62 | MEN1 (0.41) | IDO1NQO1MEN1ALDH1A1MAPT | |
| SCHEMBL8029969 | 0.62 | MEN1 (0.41) | IDO1NQO1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315551-A1 | 2-ALKYLCARBONYL[2,3-b]FURAN-4,9-DIONE PRODUCTION METHOD AND PRODUCTION INTERMEDIATE THEREFOR | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315551-A1 | 2-ALKYLCARBONYL[2,3-b]FURAN-4,9-DIONE PRODUCTION METHOD AND PRODUCTION INTERMEDIATE THEREFOR | WEE2, DHPS, WEE1 | IDO1 2501/4885NQO1 7/4885MEN1 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.