Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | AXL | P30530 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149346 | 1.00 | KDM4E (0.56) | KDM4EAXLCYP1A2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27672178 | 0.98 | KDM4E (0.55) | KDM4EAXLCYP1A2MEN1ALDH1A1 | |
| SCHEMBL2814713 | 0.91 | AXL (0.47) | KDM4EAXLGSK3AGSK3BASPH | |
| SCHEMBL29457338 | 0.87 | KDM4E (0.41) | KDM4EAXLALDH1A1KMT2ACSNK2A1 | |
| SCHEMBL28904824 | 0.87 | KDM4E (0.41) | KDM4EAXLALDH1A1KMT2ACSNK2A1 | |
| SCHEMBL7535408 | 0.84 | AXL (0.58) | KDM4EAXL | |
| SCHEMBL31024826 | 0.82 | CSNK2A1 (0.43) | KDM4EAXLCYP1A2MEN1ALDH1A1 | |
| SCHEMBL10131672 | 0.82 | CSNK2A1 (0.49) | KDM4EAXLCYP1A2MEN1ALDH1A1 | |
| SCHEMBL28904865 | 0.80 | ALDH1A1 (0.37) | KDM4EAXLALDH1A1KMT2AGSK3A | |
| SCHEMBL29980339 | 0.79 | ALDH1A1 (0.37) | KDM4EALDH1A1KMT2AGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520422-B | Novel pyridonecarboxylic acid derivative or salt thereof | 涌永制药株式会社 | 2023-09-05 | — | — | CN | disclosed |
| CN-109689656-B | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2022-10-04 | — | — | CN | disclosed |