Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 4/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29980191 | 0.86 | ULK1 (0.41) | ALDH1A1KMT2AADORA2AADORA1DYRK1A | |
| SCHEMBL29980016 | 0.85 | GSK3B (0.38) | ALDH1A1KMT2AKDM4EADORA2AADORA1 | |
| SCHEMBL28904865 | 0.84 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4EADORA2AADORA1 | |
| SCHEMBL29979783 | 0.79 | KDM4E (0.56) | ALDH1A1KMT2AKDM4EGSK3AGSK3B | |
| SCHEMBL9149346 | 0.79 | KDM4E (0.56) | ALDH1A1KMT2AKDM4EGSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL27672178 | 0.78 | KDM4E (0.55) | ALDH1A1KMT2AKDM4EGSK3AGSK3B | |
| SCHEMBL28904824 | 0.78 | KDM4E (0.41) | ALDH1A1KMT2AKDM4ECLK1DYRK1A | |
| SCHEMBL29457338 | 0.78 | KDM4E (0.41) | ALDH1A1KMT2AKDM4ECLK1DYRK1A | |
| SCHEMBL29980316 | 0.77 | SYK (0.37) | ALDH1A1KMT2AADORA2AADORA1 | |
| SCHEMBL2814713 | 0.72 | AXL (0.47) | KDM4ECLK1DYRK1AGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689656-B | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2022-10-04 | — | — | CN | disclosed |