SCHEMBL29979893

SCHEMBL29979893

CC1Cc2ccc(C(C)(C)C)cc2C1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.62
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 1/20 0.43
PLA2G1B P04054 1/20 0.43
NFKB1 P19838 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
CYP19A1 P11511 1/20 0.40
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HDAC4 P56524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704655 1.00 ACHE (0.62) ACHEALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL28878592 0.86 ACHE (0.53) ACHEALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL21132327 0.85 ACHE (0.63) ACHECA1CA2
SCHEMBL6204038 0.81 ALDH1A1 (0.42) ACHEALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL29893908 0.77 ACHE (1.00) ACHE
SCHEMBL2481939 0.77 ACHE (1.00) ACHE
SCHEMBL2424388 0.75 BRD4 (0.39) ACHEALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL8874748 0.75 METAP1 (0.45) ACHEALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL8601608 0.75 METAP1 (0.45) ACHEALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL6935266 0.75 ACHE (0.66) ACHECYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563438-B Organic compounds 奇华顿股份有限公司 2022-11-04 CN claimed
CN-109563438-B Organic compounds 奇华顿股份有限公司 2022-11-04 CN disclosed