Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979893 | 1.00 | ACHE (0.62) | ACHEALDH1A1NPC1PLA2G1BNFKB1 | |
| SCHEMBL28878592 | 0.86 | ACHE (0.53) | ACHEALDH1A1NPC1PLA2G1BNFKB1 | |
| SCHEMBL21132327 | 0.85 | ACHE (0.63) | ACHECA1CA2 | |
| SCHEMBL6204038 | 0.81 | ALDH1A1 (0.42) | ACHEALDH1A1NPC1PLA2G1BNFKB1 | |
| SCHEMBL29893908 | 0.77 | ACHE (1.00) | ACHE | |
| SCHEMBL2481939 | 0.77 | ACHE (1.00) | ACHE | |
| SCHEMBL2424388 | 0.75 | BRD4 (0.39) | ACHEALDH1A1NPC1PLA2G1BNFKB1 | |
| SCHEMBL8874748 | 0.75 | METAP1 (0.45) | ACHEALDH1A1NPC1PLA2G1BNFKB1 | |
| SCHEMBL8601608 | 0.75 | METAP1 (0.45) | ACHEALDH1A1NPC1PLA2G1BNFKB1 | |
| SCHEMBL6935266 | 0.75 | ACHE (0.66) | ACHECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563438-B | Organic compounds | 奇华顿股份有限公司 | 2022-11-04 | — | — | CN | claimed |
| EP-3497192-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2021-12-22 | — | — | EP | claimed |
| US-11020333-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2021-06-01 | — | — | US | claimed |
| US-20200330346-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2020-10-22 | — | — | US | claimed |
| CN-109563438-B | Organic compounds | 奇华顿股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| EP-3497192-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2021-12-22 | — | — | EP | disclosed |
| US-11020333-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2021-06-01 | — | — | US | disclosed |
| US-20200330346-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2020-10-22 | — | — | US | disclosed |
| EP-3497192-A2 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2019-06-19 | — | — | EP | disclosed |
| CN-109563438-A | Organic compounds | 奇华顿股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| US-9890147-B2 | 2,3-benzodiazepines | BAYER PHARMA AKTIENGESELLSHAFT (DE) | 2018-02-13 | — | — | US | disclosed |
| US-9890147-B2 | 2,3-benzodiazepines | BAYER PHARMA AKTIENGESELLSHAFT (DE) | 2018-02-13 | — | — | US | disclosed |
| US-20150203483-A1 | 2,3-BENZODIAZEPINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150203483-A1 | 2,3-BENZODIAZEPINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150203483-A1 | 2,3-BENZODIAZEPINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-07-23 | — | — | US | disclosed |
| US-RE37573-E1 | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | BASELL POLYOLEFIN GMBH (DE) | 2002-03-05 | — | — | US | disclosed |
| US-5869584-A | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0582194-B1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | disclosed |
| US-5455365-A | Metallocene compound containing substituted indenyl ligand and transition metal element from groups IVb, Vb, or VIb; addition polymerization with aluminoxane cocatalyst | HOECHST AG (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0582194-A1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200330346-A1 | ORGANIC COMPOUNDS | C5, C1S, CBR3 | ACHE 920/4885ALDH1A1 242/4885NPC1 1422/4885 |
| US-11020333-B2 | Organic compounds | C5, CBR3, C1S | ACHE 928/4885ALDH1A1 229/4885NPC1 1425/4885 |
| US-20150203483-A1 | 2,3-BENZODIAZEPINES | BRD4, BET1, BRDT | ACHE 4121/4885ALDH1A1 3159/4885NPC1 3284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.