Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678808 | 0.87 | KDM4E (0.56) | SMN1; SMN2POLBGAATP53KDM4E | |
| SCHEMBL10984209 | 0.84 | HNF4A (0.58) | SMN1; SMN2LTB4R2ALDH1A1 | |
| SCHEMBL269580 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2LTB4R2POLBGAAUSP2 | |
| SCHEMBL31344418 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2GFERLTB4R2POLBGAA | |
| SCHEMBL2744891 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2LTB4R2POLBGAAUSP2 | |
| SCHEMBL13699903 | 0.80 | ABL1 (0.47) | SMN1; SMN2GFERGAATP53HPGD | |
| SCHEMBL30473062 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2GFERLTB4R2POLBGAA | |
| SCHEMBL8305586 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2GFERLTB4R2POLBGAA | |
| SCHEMBL7179753 | 0.78 | SLC6A2 (0.54) | HDAC4HDAC2HDAC8CYP1A2CYP2D6 | |
| SCHEMBL13366166 | 0.78 | ABL1 (0.49) | SMN1; SMN2GFERTP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | MON2, ZRANB2, GRIA2 | SMN1; SMN2 3249/4885GFER 1622/4885LTB4R2 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.