Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998004 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2LTB4R2GAAPOLBTP53 | |
| SCHEMBL269580 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2LTB4R2GAAPOLBTP53 | |
| SCHEMBL3642592 | 0.77 | ALOX15 (0.58) | SMN1; SMN2KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2744891 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2LTB4R2GAAPOLBTP53 | |
| SCHEMBL30473062 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2LTB4R2GAAPOLBTP53 | |
| Pyrrole SCHEMBL1260091 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2LTB4R2GAAPOLBTP53 | |
| SCHEMBL30786197 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2LTB4R2GAAPOLBTP53 | |
| SCHEMBL10489884 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAPOLBTP53USP2 | |
| SCHEMBL8306842 | 0.73 | HNF4A (0.51) | SMN1; SMN2PTPN1ALDH1A1MEN1LMNA | |
| SCHEMBL5219162 | 0.71 | POLB (0.55) | SMN1; SMN2LTB4R2GAAPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914317-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 1999-05-12 | — | — | EP | claimed |
| WO-1998052926-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-11-26 | — | — | WO | claimed |