Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.43 |
| ▸ | OGA | O60502 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288038 | 0.76 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL300262 | 0.72 | EDNRA (0.42) | TRPV1OGAEDNRA | |
| SCHEMBL300327 | 0.69 | TRPV1 (0.41) | TRPV1OGAEDNRA | |
| SCHEMBL5717640 | 0.65 | PTGS2 (0.59) | OGAALDH1A1EDNRA | |
| SCHEMBL24893823 | 0.65 | PTGS1 (0.52) | OGAALDH1A1 | |
| SCHEMBL24893797 | 0.65 | PTGS1 (0.52) | OGAALDH1A1 | |
| SCHEMBL24893808 | 0.65 | PTGS1 (0.52) | OGAALDH1A1 | |
| SCHEMBL5191011 | 0.64 | MME (0.55) | ALDH1A1EDNRA | |
| SCHEMBL8479189 | 0.64 | EDNRB (0.52) | TRPV1EDNRA | |
| SCHEMBL8035766 | 0.63 | PTGS1 (0.59) | OGAKDM4EALDH1A1MCL1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427436-A1 | SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127855-A1 | SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2010-11-11 | — | — | WO | disclosed |