Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23499456 | 0.90 | BRD4 (0.36) | JAK2BTKBRD4CREBBP | |
| SCHEMBL29993835 | 0.85 | — | — | |
| SCHEMBL29979440 | 0.82 | — | — | |
| SCHEMBL24740796 | 0.77 | JAK2 (0.33) | JAK2BTK | |
| SCHEMBL21631597 | 0.75 | PTPN11 (0.34) | — | |
| SCHEMBL21653820 | 0.75 | LPL (0.33) | JAK2BTK | |
| SCHEMBL21653818 | 0.73 | UCHL1 (0.33) | — | |
| SCHEMBL24740793 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL1087847 | 0.71 | JAK2 (0.36) | JAK2BTKBRD4CREBBP | |
| SCHEMBL31387338 | 0.71 | IRAK4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212819-A1 | INDAZOLE DERIVATIVES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2022-10-06 | — | — | WO | disclosed |