Cadaverine Tartrate — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CHRM1 CHRM2 CHRM3 CHRM4 ESR1 ESR2 GABRA1 GABRB1 GABRG2 GBA1 HRH1 HTR1D HTR2A OPRD1 OPRK1 OPRM1 SLC6A2 SLC6A3 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	2/20	0.48

▸	MMP8	P22894	2/20	0.40

▸	MMP1	P03956	1/20	0.40

▸	EPHX1	P07099	1/20	0.38

▸	MMP2	P08253	1/20	0.38

▸	NFKB1	P19838	1/20	0.36

▸	CYP2C19	P33261	1/20	0.36

▸	ALDH1A1	P00352	2/20	0.36

▸	GRM2	Q14416	1/20	0.36

▸	SLC1A3	P43003	2/20	0.35

▸	SLC1A2	P43004	2/20	0.35

▸	SLC1A1	P43005	2/20	0.35

▸	CES2	O00748	1/20	0.35

▸	CES1	P23141	1/20	0.35

▸	GRIK1	P39086	1/20	0.34

▸	TP53	P04637	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Cadaverine Tartrate SCHEMBL1543395	0.84	TSHR (0.46)	TSHRNFKB1CYP2C19GRM2SLC1A3
Cadaverine Tartrate SCHEMBL1543394	0.84	TSHR (0.46)	TSHRNFKB1CYP2C19GRM2SLC1A3
Cadaverine Tartrate SCHEMBL1543404	0.84	TSHR (0.46)	TSHRNFKB1CYP2C19GRM2SLC1A3
Cyclohexylamine SCHEMBL11565837	0.84	TP53 (0.50)	MMP8MMP1EPHX1MMP2ALDH1A1
Tartaric Acid SCHEMBL30276688	0.83	TSHR (0.50)	TSHRMMP8MMP1EPHX1MMP2
Cadaverine Tartrate SCHEMBL1155812	0.83	TSHR (0.50)	TSHRMMP8MMP1EPHX1MMP2
Cadaverine Tartrate SCHEMBL17439178	0.83	TSHR (0.50)	TSHRMMP8MMP1EPHX1MMP2
Cadaverine Tartrate SCHEMBL918361	0.83	TSHR (0.50)	TSHRMMP8MMP1EPHX1MMP2
Cadaverine Tartrate SCHEMBL30899742	0.83	TSHR (0.50)	TSHRMMP8MMP1EPHX1MMP2
Cadaverine Tartrate SCHEMBL30899743	0.83	TSHR (0.50)	TSHRMMP8MMP1EPHX1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100197841-A1	HYDROXY ACID AMINE SALT, METHOD FOR PRODUCING THE SAME, AND RUBBER COMPOSITION CONTAINING THE SAME	THE YOKOHAMA RUBBER CO., LTD.	2010-08-05	—	—	US	disclosed
CN-101754946-A	Hydroxy acid amine salt, method for producing the same, and rubber composition containing the same	YOKOHAMA RUBBER CO LTD	2010-06-23	—	—	CN	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20100197841-A1	HYDROXY ACID AMINE SALT, METHOD FOR PRODUCING THE SAME, AND RUBBER COMPOSITION CONTAINING THE SAME	HRH3, HRH2, HRH4	TSHR 2289/4885MMP8 2887/4885MMP1 3003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.