Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967837 | 0.83 | PIM1 (0.39) | ERN1CYP2A6TDP1ALDH1A1 | |
| SCHEMBL4598834 | 0.79 | ALDH1A1 (0.47) | ERN1TDP1ALDH1A1 | |
| SCHEMBL3795481 | 0.79 | ERN1 (0.36) | ERN1HSD17B10CYP2A6TDP1ALDH1A1 | |
| SCHEMBL18138665 | 0.76 | FFAR4 (0.44) | — | |
| SCHEMBL30640 | 0.76 | FFAR1 (0.45) | ERN1ALDH1A1PTGDR2 | |
| SCHEMBL11077336 | 0.74 | HSD17B10 (0.65) | TTRHSD17B10TDP1CA12CA1 | |
| SCHEMBL27324629 | 0.74 | ERN1 (0.49) | ERN1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL15015817 | 0.73 | PDE2A (0.37) | ERN1PTGDR2 | |
| SCHEMBL155042 | 0.73 | ERN1 (0.57) | ERN1CYP2A6TDP1ALDH1A1PTGDR2 | |
| SCHEMBL1124809 | 0.73 | HSD17B10 (0.52) | ERN1TTRHSD17B10TDP1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |