Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | HTR1D | P28221 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640 | 0.80 | FFAR1 (0.45) | ERN1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29985 | 0.79 | ERN1 (0.47) | ERN1CYP2A6ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4967837 | 0.78 | PIM1 (0.39) | ERN1CYP2A6MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14128729 | 0.78 | ERN1 (0.43) | ERN1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4598834 | 0.77 | ALDH1A1 (0.47) | ERN1MAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL21338176 | 0.74 | TDP1 (0.55) | ERN1CYP2A6MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL320553 | 0.74 | TDP1 (0.41) | ERN1CYP2A6MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18138665 | 0.74 | FFAR4 (0.44) | CYP2C9PDE2AKCNH2 | |
| SCHEMBL4859993 | 0.73 | ALDH1A1 (0.53) | CYP2A6MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15015817 | 0.71 | PDE2A (0.37) | ERN1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230907-A1 | BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE | Theracos, Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009076550-A1 | BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE | THERACOS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |