Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | PDE2A | O00408 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30453 | 0.85 | LMNA (0.40) | ERN1PDE2AALDH1A1MAPTKMT2A | |
| SCHEMBL4598834 | 0.85 | ALDH1A1 (0.47) | ERN1PDE2AALDH1A1MAPTKDM4E | |
| SCHEMBL19252821 | 0.84 | FFAR4 (0.45) | FFAR1FFAR4ERN1PDE2AALDH1A1 | |
| SCHEMBL15015817 | 0.84 | PDE2A (0.37) | FFAR1FFAR4ERN1PDE2APTGDR2 | |
| SCHEMBL3795481 | 0.80 | ERN1 (0.36) | ERN1PDE2AALDH1A1MAPTKMT2A | |
| SCHEMBL18138665 | 0.79 | FFAR4 (0.44) | FFAR1FFAR4PDE2A | |
| SCHEMBL6319246 | 0.77 | ERN1 (0.54) | ERN1ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL29985 | 0.76 | ERN1 (0.47) | ERN1ALDH1A1PTGDR2 | |
| SCHEMBL29893480 | 0.76 | FFAR4 (0.56) | FFAR1FFAR4ALDH1A1MAPTKMT2A | |
| Formaldehyde SCHEMBL29161042 | 0.75 | FFAR4 (0.55) | FFAR1FFAR4ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |